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My mom has chronic CDIF since January this year. (3 confirmed lab tests & 4 times treated with vanco + flaje antibotics ). She has been in and out of hospital, then acute rehab, then back to AL. Not to mention multiple falls and has alzheimer's, PAD, COD, spinal stenosis, degenerated disc disease, 2 reputured discs, incontinencence, depression, cannot hear, drop foot and signs of parkinson as well. This last time she was in the hospital for the longest time, 8 days, prior to release. Every trip to hospital is getting longer and longer stay. We have seen a specialist, who suggested a higher dose of antibotics and/or fecal transplant (I know gross). The transplant (donor required) is a procedure done as colonoscopy. My mom cannot go through the "prep" work of colonoscopy, since she is so weak. She is on the higher dose of antibotics, plus the probotics, now. There are experimental frozen fecal pills- yaks...but cannot find any physcians who would treat her in that manner.


How can an elderly individual continue to be on an antibiotic for CDIF?


It's horrible what my mother is experiencing and I am at my 'wits' end on what to do with this situation. Any advice is appreciated.

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My mother had this treatment 5 years ago for C. diff. colitis. Think hard about how this would improve your mother's quality of life. It cleared up the C.diff for my mother but she was left so weakened by the infection and other issues that she was left bedridden as a result. She is still lucid but family members have hinted to me that I should not have arranged the treatment with my mother's consultant because of her quality of life.

My mother's treatment was one of the first and she did not have to "drink" anything. It was done via tube into the digestive system. The donor may or may not be a family member. A family member's microbiome (gut bacteria) may be too similar to that of the person getting the treatment for it to be seriously effective. If you are in the US an option to get frozen standardised samples might be an option.

Consider talking to her medical team about how she would benefit from the treatment and what she would want before putting her through it. The treatment has a high success rate and it may clear up your mother's infection but it sounds like she was suffering a lot before she even got the infection.
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anonymous683453 Jul 2019
My roommate, with severe COPD, heart failure, and on dialysis for almost four years, contracted cdiff after getting fitted for the internal tubing for home dialysis. He also contracted an internal fungus disease that nearly killed him. The treatment for that gave him vivid hallucinations and delusions. The tubing was removed and he is back in regular dialysis.
After rounds of antibiotics and hospital stays, he did get the fecal transplant that has stopped the cdiff. However, he is now in such a weakened state, he has no quality of life. He is barely walking and just sits in his recliner all day sleeping mostly and watching a little tv. Back and forth to the bathroom and out to car for trips to dialysis is all he can barely manage to do. Has been on oxygen 24/7 for about 5 years. What is the point of this? His mind is even starting to fail now.
IF he gets any worse, he has to go to a nursing home. I cannot take care of an invalid with all the other things I have to do running a ranch and it isn't my obligation, he does have some long distance family. I told him that a few days ago. He knows if he falls again he has to go to a nursing home, the doctors told him that.
Now he has fluid around his left lung and heart. He thinks he will be much better once that is drawn off. It's always another treatment that he thinks will improve his health. Meanwhile, his health continues to decline, rapidly over the past 12 months.

I do have some great neighbors that can take him into town to dialysis right now. But Where does it end?
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I’ve had stomach issues since childhood. When I took popular probiotics like Align, I got no results. When my doctor put me on a physicians brand, it made a big difference so the quality of the probiotics is very important. In addition to taking probiotics ( or foods like sauerkraut as another person mentioned), I recently learned that we have to feed our good gut bacteria and stop feeding our bad gut bacteria with refined, sugary foods. Good gut bacteria needs fiber and “prebiotic” foods. You can google. My doctor also gives me a supplement that contains L-glutamine which can help prevent infection and inflammation in the gut. I know this doesn’t answer your main question but maybe these things will help support your Mom’s recovery. Good luck! I hope your Mom is better soon!
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Harpcat Jul 2019
I’m interested to know what the name is of the supplement with L-glutamine. Thanks!
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The longer a person is on antibiotics, the less effective they become. I think it's time to contact hospice. Your mother has no quality of life with so many illnesses. I know it's hard to let go but there comes a time when you have to realize the person is going through hell and there is no hope.
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slp1684 Jul 2019
Wow, quite a decision that is difficult and without family support (older sisters who do nothing with my moms care). Wonder if I am not ready to "let go". For some reason, I cannot give up yet.
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Fecal transplants are successful. From what I understand the donor is a family member. While it is gross, it is a treatment option.

C.diff will be hard to eradicate as your mother has compromised immune system as well as multiple comorbids that make her a susceptible host.

The only treatment I know of is the fecal transplant. And that may not work but may be worth a try. Colonoscopy prep will be difficult. There also are diet plans for c.diff you can look up on the Internet & use as guidance.

This is such a hard situation and I wish you the best of luck.
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Yes they are very strong antibiotics. i'm a RN. How old is your mom? If she's weak and not doing well, she may be "giving up" I know myself, if I'm up in years in that state, I don't want anyone giving me a colonoscopy! Honor your mom's wishes if she's up in age and does not want this these procedures going on. How would you feel.? If she says "no", then it's "no" Period. God bless you, give you peace in your situation caring for mom.
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Have the tried Dificid? I had treatment resistant c-diff for 9 months and it nearly killed me. Finally my doctor put me a two month course of Dificid and that did the trick (flagyl and vancomycin did nothing). I would gladly have done a fecal transplant if needed. C-diff is no joke. Its been 14 months since it was irradicated and I'm still fighting to get muscle mass and strength back. I'm sorry your mom is suffering with this dreadful condition.
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What’s her age? I agree with hospice!!
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Hospice.
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Talk to the doctor about the possibility of doing the transplant without the bowel prep. The purpose of the thourough cleansing of the bowel before a colonoscoppy is so that the doctor can visualize the lining of the bowel. That can't be done if the view is obscured by fecal material. But for the fecal transplant, visualization is not part of the goal. Cleaning out the infected material is preferable, but if the patient has C Dif they probably don'thave much contents in the bowel. Perhaps giving them the transplant without prep, maybe effective . If the other option is doing nothing, why not try.
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When my Mother needed a colonoscopy and couldn't do prep I was allowed to do enemas until "clear". Basically no bowel material left in bowel. Dr. said she was cleaner than anyone he had do the actual prep. Also if it is just for the fecal transplant she wouldn't need to be cleaned out. See if they will do with just enema prep.
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